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Best-Selling Psychiatrist Dr. Daniel Amen to Release "Change Your Brain, Change Your Pain," Unlocking the Link Between Thoughts and Healing


Published: Nov 07, 2025 12:03 AM EST

One of the world's leading experts on the brain, Daniel G. Amen, MD, will release his groundbreaking new book, Change Your Brain, Change Your Pain: Break Free from the Doom Loop of Physical and Emotional Suffering (HarperCollins) December 2, 2025. In this insightful release, Dr. Amen uncovers how chronic physical and emotional pain share the same neurological roots, and how understanding and healing the brain can help readers find lasting freedom from pain.

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In the United States alone, one in five adults experiences chronic pain. For too long, when doctors couldn't find a clear medical cause, patients were told dismissively, "it's all in your head." Today, research shows that our somatic responses to trauma, anxiety, and depression create real suffering-and that physical pain can also trigger trauma, anxiety, and depression.

Dr. Amen calls this cycle "the doom loop," which describes the dance between physical and emotional pain that keeps millions trapped in suffering. But, as he explains, we can shift from the doom loop to a healing loop. Drawing from over 250,000 brain scans conducted at Amen Clinics and decades of clinical research, Dr. Amen provides practical, brain-based tools to help readers heal at every level.

In Change Your Brain, Change Your Pain, Dr. Amen reveals:

  • Pain-producing vs. pain-soothing thought patterns
  • How muscle tension and trauma affect brain pathways-and how calmness and clarity restore them
  • The role of medical and nutraceutical tools in calming overactive pain circuits
  • How diet, exercise, meditation, and breathwork can transform pain into healing

"Our current approach to understanding and treating pain is misguided," said Dr. Amen. "To be free of pain, your brain must be as healthy as possible-physically, emotionally, psychologically, and spiritually."

Change Your Brain, Change Your Pain challenges the conventional approach to pain management, offering a healthier, more holistic alternative that reduces dependency on medication and surgery while improving long-term outcomes. Dr. Amen's framework empowers readers to transform their relationship with pain and discover lasting relief through brain health.

Change Your Brain, Change Your Pain will be available wherever books are sold on December 2, 2025.

For media inquiries or to request a copy or an interview with Dr. Amen, please email  press@jdaworldwide.com.